Re: Gynaecological effects of tamoxifen
نویسندگان
چکیده
منابع مشابه
Re: Gynaecological effects of tamoxifen.
I have read with considerable interest the paper by N Yukawa et al concerning intra-alveolar haemorrhage in infant deaths, 1 and Professor Berry's editorial response. I also applaud the authors' ambition to bring some scientific objectivity to this controversial issue. The results of their investigation are extremely diYcult to interpret, however, because the authors have carried out mor-phomet...
متن کاملRe: Effects of the antiestrogens tamoxifen, toremifene, and ICI 182,780 on endometrial cancer growth.
BACKGROUND Tamoxifen has been shown to promote the growth of human endometrial tumors implanted in athymic mice, and it has been associated with a twofold to threefold increase in endometrial cancer. Toremifene, a chlorinated derivative of tamoxifen, and ICI 182,780, a pure antiestrogen, are two new antiestrogens being developed for the treatment of breast cancer. The effects of these drugs on ...
متن کاملEffects of Tamoxifen on Morphological and Ultrastructural Aspects of Developing Hippocampus of Rat
Background: Tamoxifen treatment induced cell death in the hippocampus formation of the prenatal and postnatal rat. The present study delineates the effect of tamoxifen on developing hippocampus in prenatal, postnatal and full term neonate rats received certain doses of the partial antagonist tamoxifen. Methods: After perfusion and fixation, the brains were removed and processed for light and e...
متن کاملEffects of tamoxifen on urinary incontinence
RATIONALE Tamoxifen has been used in women with hormone receptor-positive breast cancer and has been shown to successfully reduce both recurrence and mortality. On the contrary, long-term use of tamoxifen has hormone-related urogenital side effects which decrease the quality of life of the patients. PATIENT CONCERNS In this case report, we present a breast cancer patient receiving tamoxifen w...
متن کاملRe: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine.
BACKGROUND Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active metabolites by cytochrome P450 (CYP) enzymes. Selective serotonin reuptake inhibitors (SSRIs), which are often prescribed to alleviate tamoxifen-associated hot flashes, can inhibit CYPs. In a prospective clinical trial, we tested the effects of coadministration of tamoxifen...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2000
ISSN: 0021-9746
DOI: 10.1136/jcp.53.6.484-a